Imaging has always been regarded as one of the strengths of the Royal North Shore campus. It was the site of the first clinical MRI scanner in Australia. Today, researchers have access to state-of-the-art medical imaging devices in both the public and private hospitals and the necessary research support teams to help them analyse their data. In addition, closely aligned with imaging, the Kolling Building houses a small animal irradiator (SARRP) which can be used for cell and preclinical radiation experimentation.

Sydney Vital researchers make extensive use of the precinct’s imaging resources. The Translational Theranostics flagship has active projects in the use of whole-body PET functional imaging as a prognostic biomarker for neuroendocrine tumours and in prostate cancer. The nano oncology flagship uses a combination of MRI and PET imaging to identify metastatic lymph node disease in colorectal cancers. Other trials currently recruiting are using early imaging with PET to identify response to neoadjuvant chemotherapy, with a view to changing the treatment if it is not proving successful.

The figure shows metastatic prostate cancer that has spread to the spine and skull.